AdvanceBio EC-C18 Series

These PEEK-lined columns alleviate interactions with stainless steel surfaces, which can lead to additional aggregation. They feature a narrow 2.1 mm internal diameter for operating flow rates of just 0.05 to 0.10 mL/min, and are ideal for sensitive, native-mode protein analysis. What’s more, their inert hydrophilic coating allows you to use volatile mobile phases in lower concentrations while minimizing nonspecific interactions.

The AdvanceBio EC-C18 Series is a fully end-capped C18 silica stationary phase features excellent retention characteristics for a wide range of peptides typically found in a digested protein. What’s more, their superficially porous Poroshell particles offer high performance without exceptional operating pressures. We recommend EC-C18 columns for applications where stainless steel columns might interact with components like phosphorylated peptides—or increase on-column oxidation of susceptible amino acids like methionine.