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SIELC Technologies has developed a line of Newcrom columns, a mixed-mode column based on a new type of bonded stationary phase. This set includes four mixed-mode columns with anion and cation exchange properties and differing ionic capacities. All four columns are both reverse-phase (RP) type and ion-exchange (IE) type. What makes Newcrom columns special? It is the position of the ion-exchange groups in the ligand structure bonded to the silica surface.