Exmere’s first polar embedded phase, the Avanti Quattro, gives excellent performance for all compounds at low pH and exceptional performance for bases at neutral pH. To compliment its performance envelope, we have produced an alkylamide phase based on our Avanti BDS. The Alkam phase utilises our highly purified, base deactivated, 145Å Avanti BDS which is carefully bonded with a stable alkyl amide phase of medium chainlength using decanoic acid. This results in a phase which shows reduced base retention compared with an alkyl bonded phase on the same silica. Peak shape for bases is also improved over the alkyl phase while the problem of tailing with acids which is sometimes encountered with amide phases, is overcome by the careful bonding procedure.
