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MonoCap Trap columns have a relatively big throughpore and workable at a high flow rate such as 10 μL/min. This benefit makes MonoCap Trap columns to be appropriate for on-line preconcentration or desalting of protein and peptide samples prior to HPLC separation with mass spectrometry detection. End-fittings are 1/16” (10-32 UNF). 1/32” end-fittings are also available upon request.
GL Sciences’ MonoCap series, created synthetically via sol-gel method, and an octadecyl silane chemically bonded, has a very uniform three dimensional structure that shows excellent reproducibility from batch-tobatch.
The solid structure of GL Sciences’ monolithic silica eliminates the need for frits or filters at the ends of the column, thereby reducing dead volume that might otherwise lead to band broadening or sample recovery. The high porosity of our monolithic silica allows high flow rates to be used without loss of resolutionor creation of high operating pressure. An
optimized balance of throughpores and mesopores provides the critically importantcombination of efficiency, separation speed, large volume sample-loading, and small volume