Internal Surface Reversed Phase (ISRP)

Internal Surface Reversed Phase developed by Dr. Thomas Pinkerton, this material was created specifically for the direct analysis of drugs in serum without extensive sample preparation. The result was a new phase that allows for chromatographic separations without interference by protein adsorption.

Regis ISRP GFF II Continuing product improvement efforts resulted in the development of the ISRP GFF II, a second generation phase with an improved bonding process—bonding the GFF peptide to the silica surface through a monofunctional glycidoxypropyl linkage rather than the original trifunctional linkage. This resulted in the following improvements:

• Increased sample retention
• Higher column efficiency
• Greater batch-to-batch reproducibility