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PC HILIC is a silica-based HILIC column with phosphorylcholine (PC) group. The superhydrophilic character of PC was taken advantage of in preparing an optimum stationary phase for HILIC mode separation. Polar, hydrophilic, and charged compounds, which are hard to handle in reversed-phase mode, are expected to show adequate retention with PC HILIC. Phosphorylcholine (PC) is a partial structure of phosphatidylcholine (lecitin), one of the phospholipids forming cell membranes. PC has a betaine structure and shows high hydrophilicity, biocompatibility, and inhibitory eff ect of protein adhesion. Its superhydrophilic character is suitable to the application as a HILIC phase.
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Osaka Soda HPLC Catalog
