COSMOSIL C18-EB 120Å (Analysis of Basic Compounds)

Conventionally end-capped C18 columns still have many residual silanol groups on the silica surface of stationary phase that can form ionic bonds with basic compounds. The resulting peak tailing makes accurate quantification of analytes difficult, especially in trace analyses. COSMOSIL 3C18-EB with a better end-capping treatment offers improved peak shape and separation particularly for basic compounds. COSMOSIL 3C18-EB produces sharp peaks using ammonium acetate buffer in LC-MS. 3C18-EB has excellent synthesis reproducibility and column-to-column reproducibility, so it is applicable in routine analysis such as quality control of drugs.

• Monomeric bonded Octadecyl group (USP L1)
• Near-perfect endcapping
• approx. 14.5% Carbon Content
• Excellent for Basic compounds
• Suitable for drug analysis

COSMOSIL 3C18-EB Brochure