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In areas like drug discovery where target compounds are increasingly polar, it is critical to have a reversed-phase column that performs well under aqueous conditions. Retention is critical, but cannot come with troublesome secondary interactions. From the collapse-resistant pore structure of our base silica, to the "wettability" engineered into the bonded phases, Polaris columns have been designed for high aqueous conditions. The combination of high phase density bonding, ultra pure silica, and silanol shielding leads to excellent peak shape among polar-modified columns.
Polaris C8-A offers an alternative selectivity to standard C8 phases and has a lower hydrophobicity than Polaris C18-A, ideal for polar samples, or faster overall analysis times.