Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns provide good peak shape over a wide pH range (2-9) for additional method development flexibility with one family of columns.
Agilent ZORBAX Eclipse XDB columns can be used for method development at low pH (2-3) and the same column can be used for method development in the mid pH (6-8) region. In the mid pH region residual silanols are more active and tailing interactions are ore likely. To overcome these interactions, Eclipse XDB columns are eXtra Densely Bonded and double endcapped through a proprietary process to cover as many active silanols as possible. The result is superior peak shape of basic compounds from pH 2-9. Eclipse XDB columns are available in 1.8µm, 3.5µm, 5µm and 7μm particle sizes for high speed, high resolution, analytical and prep scale separations.