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Bond Elut Plexa PCX is a further milestone in the development of simple and robust SPE methods. Plexa PCX uses a polymeric cation exchange resin that combines the outstanding properties of Bond Elut Plexa – superior flow characteristics and improved analytical performance – with strong cation exchange functionalities. This mixed-mode SPE sorbent removed neutral and acidic interferences from the matrix, concentrates basic analytes and therefore improves sensitivity in the determination of basic compounds.
The Plexa PCX particles are near mono-dispersed, resulting in homogenous packing. Reproducible results are the norm, with very good tube-to-tube and well- to-well performance. Ion suppression is reduced because the highly polar, hydroxylated polymer surface is entirely amide-free and does not provide binding sites for endogenous species such as proteins and lipids. Plexa PCX comes with a simple, single method approach for basic drugs that offers improved recoveries, cleaner extracts and reduced method development time and cost. Flow rate is improved because Plexa PCX particles have much narrower particle size distribution with no fines to cause blockages.> |