SampliQ C8/Si-SCX

The use of mixed-mode stationary phases is widely accepted for the extraction of basic drugs from biological fluids. The SampliQ Mixed-Mode Reversed-Phase SPE product consists of an alkyl phase (C8) and a strong cation exchange phase (Si-SCX) in an optimized ratio that provides a dual retention mechanism. The C8 functionality interacts with the hydrophobic portions of an analyte while the Si-SCX functionality interacts with the protonated amine portion. The strong analyte interactions allow the use of more rigorous washing conditions to eliminate co-extractables that might interfere with UV detection or cause ion suppression effects in LC-MS. The SampliQ Mixed-Mode phase is manufactured with trifunctional silanes allowing for maximum stability and low leachability. The phase is non-endcapped which gives some added interaction between residual silanols and polar analytes helping to provide added retention characteristics.

Part Number

Products

Price

Qty / Buy
AT-5982-1911 SampliQ C8/Si-SCX, 100mg, 1ml, pk.100 price on request
AT-5982-1932 SampliQ C8/Si-SCX, 200mg, 3ml, pk.50 price on request
AT-5982-1965 SampliQ C8/Si-SCX, 500mg, 6ml, pk.30 price on request