Reversed phase sorbents are non-polar, and will be used to retain (extract) non-
polar analytes. For reversed phase sorbents, retention decreases as the solvent
becomes more non-polar
SampliQ C18EC products are based on bonded, endcapped, reversed-phase
octadecylsilane (ODS) silica gel particles. The non-polar sorbent is endcapped
(EC), reducing polar secondary interactions associated with surface silanol
groups. Non-polar analytes should be more strongly retained compared
with non-endcapped SampliQ C18 products. SampliQ C18EC has
a 25% carbon loading.
Figure: Structure of C18 silane and trimethyl silyl
endcapping group, covalently bonded to
the surface of a silica particle
