At Princeton Chromatography we have led the way in developing a series of novel amide, urea and pyridine phases that enhance the capability of the SFC technique by providing increased selectivity and loading capacity. Princeton Chromatography was the first company to develop and market the popular 2-Ethylpyridine phase which was launched in 2001 and later the 4-Ethylpyridine phase. PrincetonSFC 2-Ethylpyridine is non-endcapped and has become the column of choice for achiral SFC analysis of basic compounds. This phase generally requires no addition of amines to the eluent, producing excellent peak shape and reproducibility.
A diol phase is a popular and versatile stationary phase for SFC. We have also developed several different hydroxylated stationary phases, most notably the HA Series, which offer excellent selectivity and retention characteristics. These phases are a great starting point for impurity analysis.