Low-pressure GC MS

Low-pressure GC-MS (LPGC-MS) is a technique that uses the MS vacuum system, along with a specially designed column setup, to lower pressure inside the entire column, thereby significantly speeding up analysis. By using a 0.53 mm analytical column that is inserted directly into the MS and a flow restrictor on the GC inlet side, low pressure can be maintained throughout 0.53 mm analytical column. Using LPGC-MS, some efficiency is traded for speed, but because a mass spectrometer is used, most coeluting components can be deconvoluted by the MS.

Restek Low-Pressure GC-MS (LPGC-MS) Brochure