GL Sciences MonoTip is available to purify and enrich femto mole to micro mole levels of peptides and proteins before MALDIMS and LC-MS analys is . Monolithic silica is consisted of double pore structure with having continuous throughpores and silica skeletons which have meso-pores . Silica skeletons make network structure below. The unique monolithic silica structure contributes to low pressure drop and strong analyte-to-surface interactions. In MonoTip, Monolithic silica is directly attached to the inner surface of the 10µl tip and 200µl tip. MonoTip correspond to small sample volume and large volume required by scientist.