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HP-C18(2) uses a proprietary ODS bonding chemistry to a high surface area silica gel to achieve long retention time and high loading capability. The ODS density is specially designed to achieve optimal selectivity for both hydrophobic and hydrophilic compounds. The proprietary endcapping chemistry maximizes consumption of silanol groups on the silica surface, and minimizes the free silanol groups to undetectable level. Such unique bonding chemistry allows the phase to achieve high peak symmetry, even for basic compounds. HP-C18(2) phase is compatible with 100% aqueous mobile phases.
Small Molecule Separations Catalog.pdf
