For UHPLC, suitable packaging materials and columns must satisfy certain claims. Short analysis times are achieved with small column dimensions, the desired high chromatographic resolution however, cannot be achieved with the particle sizes used normally in HPLC. For the UHPLC therefore, silica gel with particle diameters less than 2µm have come up (“sub-2-µm particles”). Very high plate numbers are achieved with these bulk materials, leading to a very high resolution.
With U-VDSpher columns, VDS optilab offers the ideal solution for UHPLC applications. The different U-VDSpher separation phases have the required small particle size of 1.8 µm and the columns are packed in a special production process. These are therefore, ideal for the requirements of UHPLC.