Agilent OmniSpher Series

Agilent OmniSpher is an ultra-high bonded silica designed for the analysis of mixtures containing either acidic or basic functionality that would normally tail on more traditional columns. The base silica for this column is made from ultra-high purity silica where metal ion and salt concentration is typically below 3ppm. This low concentration of ion means that secondary interactions that normally contribute to peak tailing are eliminated. That makes the Agilent OmniSpher C18 column ideal for the separation of neutral, polar, acidic, and basic compounds.

The ultra-high purity silica in the Agilent OmniSpher C18 column is a spherical particle with a very narrow particle distribution. These spherical particles allow the packing of high efficiency columns with excellent permeability and good mechanical strength. Agilent’s single step derivatization procedure in the chemical bonding of monofunctional C18 groups to the silica surface forms a uniform non-polar surface layer, contributing to the unsurpassed performance of the OmniSpher C18.