Compounds are retained on hydrophilic sorbents through polar interactions including hydrogen bonding, pi-pi or dipole-dipole interaction. These types of interactions occur when a distribution of electrons between individual atoms in functional groups is unequal, causing negative and positive polarity. Compounds typically extracted on a hydrophilic column include analytes which have polar groups, including amines, hydroxyls and carbonyls. Elution is performed by strong polar solvents.
Sorbent Specifications:
Characteristic: Hydrophobic
Organic Loading = n/a
Average Pore Size = 60Å
Surface Area = 500 m²/g
Pore Volume = 0.77 cm³/g
Application: Removes hydrophilic (polar) impurities, purification of hydrophilic (polar) compounds