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Compounds are retained on hydrophilic sorbents through polar interactions including hydrogen bonding, pi-pi or dipole-dipole interaction. These types of interactions occur when a distribution of electrons between individual atoms in functional groups is unequal, causing negative and positive polarity. Compounds typically extracted on a hydrophilic column include analytes which have polar groups, including amines, hydroxyls and carbonyls. Elution is performed by strong polar solvents.
Sorbent Specifications:
Application: Removes hydrophilic (polar) impurities, purification of hydrophilic (polar) compounds
UCT Food Safety & Environmental Product Catalog 2017