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CAPCELL CORE AQ enables analysis in reversed phase mode. It is the most suitable for the analysis of highly polar compounds which have smaller retention with conventional C18 columns. Furthermore, this column limits the influence of silanol and similar constituents deriving from the substrate with a surface of packing material coated with polymer. CAPCELL CORE AQ enables high separation of highly polar compounds.
With CAPCELL CORE AQ, we sought the bonding density of C27 group (heptacosyl group) appropriate for the 100 % aqueous mobile phase, yet still hydrophobic. As a result, we achieved stable measurement with 100% aqueous mobile phase. Compared with the C18 columns, while the analysis time for hydrophobic compounds is about one half with CAPCELL CORE AQ, the retention of polar compounds is large and separation is good.