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Agilent Eclipse Plus columns are recommended for initial method development from pH 2-9 and provide high resolution and excellent peak shape of all types of compounds. Like all Agilent Eclipse columns Eclipse Plus columns achieve superior performance through extra dense bonding and a precise double-endcapping process. But Agilent Eclipse Plus columns also feature enhanced high-performance silica, new endcapping reagents, and a unique bonding process that is optimized for the improved silica.